Lesson 3

Extracellular Matrix Injury

Key points:

1. Extracellular accumulation of proteins, carbohydrates and lipids. Mucoid swelling, fibrinoid swelling (fibrinoids). Extracellular hyaline: morphogenesis, morphological characteristics. Hyaline changes in various pathological conditions.

2. Mucous (colloidal) dystrophy. Morphological characteristics, pathogenesis. Cystic fibrosis.

3. Amyloidosis: classification, morphological characteristics.


1. Kumar, Vinay, Abul K. Abbas, and Jon C. Aster. Robbins and Cotran Pathologic Basis of Disease. Ninth edition. Philadelphia, PA: Elsevier/Saunders, 2015. P.7-64

2. Kumar, Vinay, Abul K Abbas, Jon C Aster, and Stanley L. 1915-2003 Robbins. Robbins Basic Pathology. 10th ed. Philadelphia, PA: Elsevier/Saunders, 2018. P.1-33, 51

3. Klatt, Edward C. Robbins and Cotran Atlas of Pathology. Third edition. Philadelphia, PA: Elsevier Saunders, 2015.

4. Klatt, Edward C., and Vinay Kumar. Robbins and Cotran Review of Pathology. Fourth edition. Philadelphia, PA: Elsevier Saunders, 2015. P.3-17

5. Harsh Mohan. Essential Pathology for Dental Students.Fourth edition. Jaypee Brothers,Medical Publishers Pvt. Limited, 2011. P.1-77